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Doxorubicin
Systematic (IUPAC) name
(8S,10S)-10-(4-amino-5-hydroxy-6-methyl-
tetrahydro-2H-pyran-2-yloxy)
-6,8,11-trihydroxy-8-(2-hydroxyacetyl)
-1-methoxy-7,8,9,10-tetrahydrotetracene
-5,12-dione
Identifiers
CAS number
23214-92-8
ATC code
L01DB01
PubChem
31703
DrugBank
APRD00185
Chemical data
Formula
C27H29NO11
Mol. mass
543.52 g/mol
Pharmacokinetic data
Bioavailability
5% (Oral)
Metabolism
CYP3A4
Half life
12-18.5 hours[1]
Excretion
Biliary and fecal
Therapeutic considerations
Pregnancy cat.
D(AU) D(US) Legal statusPOM(UK) ℞-only(US) Routes IntravenousDoxorubicin (trade name Adriamycin) or hydroxyldaunorubicin is a drug widely used in cancer chemotherapy. It is an anthracycline antibiotic and structurally closely related to daunomycin, and also intercalates DNA. It is commonly used in the treatment of a wide range of cancers. The drug is administered by injection. It may be sold under the brand names Adriamycin PFS, Adriamycin RDF, or Rubex.[2] Doxil is a liposome-encapsulated dosage form of doxorubicin made by Ben Venue Laboratories for Johnson & Johnson. The main benefits of this form are a reduction in cardiotoxicity. Video
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The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... doxil and tylenol low blood pressure and lipitor zoloft and blood sugar ... blood, famotidine and tylenol, zestril and tylenol, nursing and tylenol overdose, tylenol and cyanide, blood pressure water pill, crestor high blood pressure, pregnancy and tylenol pain relievers, doxil and tylenol, tylenol cold and flu medicine, phentermine and blood donations, low white blood count and buspar, tylenol and advil together, blood lisinopril pressure, beer and tylenol for ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... US-NJ: Bridgewater-Associate Manager, Rebate Management .... Ortho Biotech Products, L.P. and its worldwide affiliates market PROCRIT/EPREX/ERYPO (Epoetin alfa), used to treat anemia associated with serious chronic conditions. The company also markets DOXIL (doxorubicin HCl liposome injection) for the treatment of relapsed and refractory ovarian cancer; ORTHOCLONE OKT3 (muromonab-CD3), a monoclonal antibody used to treat organ transplant rejection; and ... |
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